SR11 - EXPLORING THE CURATIVE POTENTIAL OF GUAVA (PSIDIUM GUAJAVA) LEAVES TEA IN GLUCO- REGULATORY MARKERS AMONG TYPE 2 DIABETICS Nizwa Itrat

Nizwa Itrat, Anum Nazir, Hira Amjad, Uswa Ahmad and Ayesha Amjad

 

Objective

The study was prosecuted to elucidate the potential of guava leaves tea in abating post-prandial hyperglycemia.

 

Methodology

Current efficacy study, sample sizes of 40 human subjects were selected and fractioned into 4 treatment groups (T0, T1, T2, T3). T0 was referred as Control group and kept on anti-hyperglycemic medications only. T1 was the first treatment group and partakers of this group were asked to take 4 g of guava leaves tea post-meal once in a day. T2 was regarded as second treatment group with prescribed dose of 8 g of guava leaves tea post-meal once a day to the entrants of this group. The participators of T3 group were allocated with a standard meal plan only for hyperglycemic control. The framework designed for research trial included parameters like HbA1c, Lipid profile and the results obtained from their blood samples were investigated at Day 0, Day 30 and at Day 60 of the research trial and Random Blood Sugar (RBS) of every participant from each group was recorded after every 2 days throughout the trial span. Also, the anthropometric measurements were monitored .

 

Results & Discussion

The out-turn obtained after experimental trial showed a diminution in HbA1c from (T0 =7.00±0.107, T1= 6.00±0.107, T2= 8.10±0.107, T3= 5.62±0.107) to (T0 = 6.94±0.107, T1= 5.81±0.107, T2= 7.53± 0.107, T3= 5.48±0.107), reduction in Random Blood Sugar from (T0= 166 ±0.104, T1= 162 ±0.104, T2= 180 ±0.104, T3=151 ±0.104) to (T0 = 155 ±0.104, T1=153 ±0.104, T2= 165±0.104, T3=140±0.104) and significant curtailment in hypercholesterolemia of the treatment groups. Based upon the statistical results it can be inferred that treatment group T2 = 8 g of guava leaves tea out-matched in effectiveness than other treatment groups.

 

Conclusion

Guava leaves can be employed as part of phtyo-therapy owing to its anti- glycated, anti- hypertensive and anti hypercholesteremic activity.